Autoimmune Disease Treatment
Key Takeaways
Peptide therapies use short amino acid chains to modulate immune activity, support immune balance, and reduce inflammation in many autoimmune conditions.
Certain peptides enhance regulatory T cells, influence cytokines, and act as chemotactic factors that direct immune cells to sites of inflammation for defense and tissue repair.
Soluble antigenic peptides and other targeted peptides have shown potential to suppress autoimmune activity in preclinical models by limiting inflammatory T cell activation, especially in conditions such as psoriasis, rheumatoid arthritis, inflammatory bowel disease, and multiple sclerosis.
Mirror Plastic Surgery offers concierge-level evaluations, lab testing, and custom peptide protocols, along with education, self-injection training, and close follow-up for people living with autoimmune disease.
Mirror Plastic Surgery Peptides are available through fully personalized consultations; schedule your autoimmune-focused peptide therapy visit today.
Why Choose Mirror Plastic Surgery for Autoimmune-Focused Peptide Therapy?
Mirror Plastic Surgery provides a concierge medicine model that centers your specific autoimmune history, symptoms, and goals. Each visit allows ample time to review your medical records, clarify concerns, and build a clear plan together.
Safety, function, and then aesthetics guide every recommendation. Peptide protocols are tailored to your diagnosis, lab findings, and daily life, not built from generic templates. The practice limits daily patient volume to maintain focused, unhurried care for each person.
Stephanie DeSimone, PA-C: Focused Expertise in Autoimmune Peptide Therapies

Stephanie DeSimone, PA-C, leads peptide therapy services with a strong foundation in surgical anatomy, immune system physiology, and data-driven treatment planning. Her “less is more” philosophy extends to internal wellness, with careful dosing and stepwise adjustments instead of aggressive stacking.
She designs peptide protocols that aim to calm excessive immune activity, reduce inflammation, and support tissue repair in people with autoimmune disease. Each consultation includes education on how and why specific peptides are chosen, and how they align with your health priorities. Book an appointment with Stephanie to review options for your autoimmune condition.
How Peptide Therapies Support Autoimmune Disease Treatment
Peptides are short chains of amino acids that act as signaling molecules in the body. In autoimmune disease, targeted peptides can interact with immune cells, receptors, and cytokines to reduce excessive inflammation and support a more balanced response. These signaling effects can enhance regulatory T cells, suppress overactive immune pathways, and promote tissue repair at inflamed sites.
Immune Pathways Commonly Targeted by Peptides
Immunomodulatory peptides can either enhance or suppress immune activity, influence specific cytokines, and act as immunosuppressants in states of overactivation.
Antimicrobial peptides interact with intracellular signaling pathways and protein kinases to promote host defense while limiting pro-inflammatory cytokine production.
Host defense peptides can help suppress key pro-inflammatory cytokines such as IL-6, IL-8, and TNF-α, which frequently drive autoimmune flares.
Neuropeptide Y has been shown to inhibit pro-inflammatory cytokines and support anti-inflammatory IL-10, suggesting potential therapeutic value in autoimmune conditions.
Candidacy for Peptide Therapy in Autoimmune Disease
Good candidates are people with a confirmed or strongly suspected autoimmune diagnosis who want a medically supervised way to complement their current care. Goals often include reducing inflammation, easing symptom burden, supporting energy, and improving quality of life.
Soluble antigenic peptides have shown promise in preclinical models by limiting activation of inflammatory T cells and suppressing autoimmune responses, which supports interest in carefully selected peptide strategies under professional guidance.
Autoimmune Conditions Commonly Addressed With Peptides
Peptide therapies may be considered in a range of autoimmune and inflammatory conditions where immune modulation is a central goal. These can include:
Psoriasis and psoriatic arthritis
Rheumatoid arthritis and related inflammatory arthritides
Inflammatory bowel diseases, including Crohn’s disease and ulcerative colitis
Conditions with systemic inflammation that aggravates pain, fatigue, or organ function
Antigenic peptides have been studied in animal models of type 1 diabetes and multiple sclerosis, and KPV is often used for gut-directed inflammation, which makes it a frequent consideration in inflammatory bowel conditions.
Your Personalized Peptide Therapy Journey at Mirror Plastic Surgery
Comprehensive Consultation and Lab Evaluation
Your visit typically starts with a 30–60 minute consultation and a detailed review of your history, current diagnoses, and medications. Lab testing often includes autoimmune markers, thyroid, liver, kidney, and hormone panels to build a complete picture of your health.
Stephanie may also recommend nutrition changes, stress management strategies, and other lifestyle adjustments that support immune balance and improve peptide response. Book an appointment with Stephanie to begin your customized autoimmune peptide plan.
Designing Your Custom Peptide Protocol
After consultation and lab review, you receive a tailored peptide protocol that reflects your symptoms, diagnosis, and response goals. Peptides are sourced from vetted pharmacies with robust quality and batch testing.
Protocols may include one or more of the following, depending on your needs:
BPC-157 for systemic inflammation and tissue support
KPV for gut-specific inflammation and bowel symptoms
Other specialized peptides selected for your autoimmune profile
Most patients receive clear written instructions and support within one to two weeks of finalizing the treatment plan.
Preparing for Your Peptide Therapy
Labs, Education, and Treatment Planning
Recent lab results from the last three to six months can help streamline your evaluation, so bringing them to your visit is encouraged. If these are not available, in-depth testing is usually ordered before starting treatment.
Stephanie explains how each recommended peptide works, expected benefits, and potential risks. This conversation also covers product quality, storage, and the importance of ongoing medical supervision throughout therapy.
Recovery and Ongoing Management With Peptide Therapy
What to Expect During and After Treatment
Most autoimmune peptide therapies involve self-administered subcutaneous injections. You receive step-by-step teaching on reconstitution, injection technique, and dosing, often supported by video resources.
Follow-up occurs through text support or scheduled telemedicine visits. These check-ins allow for symptom tracking, dose adjustments, and timely responses to any questions or concerns. The long-term goal is stable immune balance and reduced flare frequency.
Symptom Improvement Timeline and Lifestyle Support
Response time varies by condition and severity. Some people with inflammatory pain notice changes within days, while others with complex autoimmune disease may require several weeks or months before clear benefits appear.
Possible outcomes include decreased inflammation, fewer or less intense flares, improved energy, and better day-to-day function. Results differ between individuals, and adherence to the protocol and healthy lifestyle habits, such as regular movement and balanced nutrition, play an important role.
Safety, Supervision, and Key Precautions
Many people assume only traditional pharmaceuticals can help autoimmune disease and may overlook the potential of carefully selected biomolecules. Peptide therapy is not a replacement for necessary medical treatment, but it can offer a complementary path when guided by an experienced clinician.
Medical supervision is essential because many peptides are not FDA-approved, and potency, purity, and dosing vary widely between unregulated products. Mirror Plastic Surgery prioritizes high-quality sourcing, appropriate dosing, and close monitoring to reduce risks associated with unsupervised or online-only peptide use.
Cost and Investment Considerations
Costs for peptide therapy depend on your diagnosis, lab needs, and the type and number of peptides included in your plan. A personalized consultation allows for an accurate estimate and helps match treatment options to your goals and budget.
Book an appointment with Stephanie to discuss pricing and determine whether autoimmune peptide therapy is appropriate for you.
Frequently Asked Questions About Peptide Therapy for Autoimmune Disease Treatment
Are peptides approved by the FDA for autoimmune disease treatment?
Many peptides used for immune support are not FDA-approved specifically for autoimmune indications. Some have been evaluated in human and animal studies for immunomodulatory effects, while others remain in earlier stages of research. At Mirror Plastic Surgery, peptides are prescribed only after an in-depth consultation, with products sourced from pharmacies that provide documented quality and batch testing.
What types of autoimmune diseases can peptide therapies address?
Peptide therapies are often considered in conditions where immune modulation and inflammation control are central treatment goals. These include psoriasis, rheumatoid arthritis, inflammatory bowel disease, and other disorders marked by systemic inflammation. Peptides such as KPV, BPC-157, and TB500 are frequently chosen to support gut health, connective tissue, and overall inflammatory burden.
Will I lose the benefits if I stop taking peptides for my autoimmune condition?
Benefits from peptide therapy typically lessen over time after discontinuation. Autoimmune activity and inflammation can return toward baseline, similar to stopping other chronic care interventions. Many patients transition to a maintenance protocol once stable improvements are reached, using the lowest effective dose and frequency under medical supervision.
How does Mirror Plastic Surgery ensure the quality of peptides for autoimmune treatment?
Mirror Plastic Surgery works only with reputable compounding pharmacies that perform rigorous testing for purity, potency, and sterility. Each batch is reviewed before use to help protect patient safety. This approach, combined with structured follow-up, supports consistent and reliable dosing for autoimmune care.
Can peptide therapies be combined with my current autoimmune medications?
Peptide therapies are often incorporated alongside existing medications, but this requires coordinated oversight. Your complete medication list, including supplements, is reviewed before starting therapy. Any adjustments to conventional drugs are made carefully and only in collaboration with your broader medical team when appropriate.
Schedule Your Autoimmune Peptide Therapy Consultation
Personalized peptide therapy at Mirror Plastic Surgery can offer an additional, targeted tool to support immune balance and symptom control in autoimmune disease. Consultations are designed to be educational, collaborative, and tailored to your specific diagnosis.
Call or text to secure your appointment today: 727-361-6515.
Mirror Plastic Surgery is conveniently located in the St. Petersburg/Tampa area at 780 4th Ave S, St. Petersburg, FL 33701.
Email: hello@mirrorplasticsurgery.com
Instagram: @mirrorplasticsurgery, @dr.akashplasticsurgery, @perfectlyplastics
Disclaimer: Results may vary from person to person. Editorial content, before and after images, and patient testimonials do not constitute a guarantee of specific results.
Disclaimer: Peptide therapy is intended for wellness and optimization purposes and is not prescribed to diagnose, treat, cure, or prevent disease unless specifically stated. Many peptides are not FDA-approved and may be used off-label. Some have limited long-term safety data, with a potential for unknown risks, complications, or desensitization with prolonged use.
